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Sofosbuvir 3',5'-Bis-(S)-phosphate CAS NO.1337482-17-3
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- Product Details
Keywords
- (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3...
Quick Details
- ProName: Sofosbuvir 3',5'-Bis-(S)-phosphate
- CasNo: 1337482-17-3
- Molecular Formula: C34H45FN4O13P2
- Appearance: Light yellow to yellow (Solid)
- Application: For research use only.
- Purity: 98.77%
- Storage: Powder:
-20°C: 3 years
4°C: 2 ... - LimitNum: 0
Superiority
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Details
Sofosbuvir 3',5'-Bis-(S)-phosphate, an impurity of PSI-7977, which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
