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URMC-099 CAS NO.1229582-33-5
- Min.Order: 1 Gram
- Payment Terms: L/C
- Product Details
Keywords
- URMC099
- URMC 099
- URMC-099
Quick Details
- ProName: URMC-099
- CasNo: 1229582-33-5
- Molecular Formula: C27H27N5
- Appearance: Solid powder
- Application: Inhibitor
- DeliveryTime: 7 days
- ProductionCapacity: 10 Kilogram/Month
- Purity: 98%
- Storage: Dry, dark and at 0 - 4 C for short ter...
- LimitNum: 1 Gram
Superiority
URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively. MLK3 activation is associated with many of the pathologic hallmarks of HAND and therefore represents a prime target for adjunctive therapy based on small-molecule kinase inhibition. www.bocsci.com/urmc-099-cas-1229582-33-5-item-470828.html
Details
URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively. MLK3 activation is associated with many of the pathologic hallmarks of HAND and therefore represents a prime target for adjunctive therapy based on small-molecule kinase inhibition. www.bocsci.com/urmc-099-cas-1229582-33-5-item-470828.html