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3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxybenzyl)-1-methylurea CAS NO.1225199-26-7
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Keywords
- Urea, N-[(3-methoxyphenyl)methyl]-N-methyl-N'-[4-(1H-pyrazol-4-yl)-2-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
- KB-81407
Quick Details
- ProName: 3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidi...
- CasNo: 1225199-26-7
- Molecular Formula: C25H31N5O3
- Application: For research use only.
- Purity: 95%
- LimitNum: 0
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Details
3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxybenzyl)-1-methylurea is a Rho kinase (ROCK) inhibitor. It had excellent enzyme and cellular potency, high kinase selectivity, high aqueous solubility, good porcine corneal penetration, and appropriate DMPK profiles for topical applications as antiglaucoma therapeutics.
