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Home > Products >  LOXO-101 (ARRY-470)

LOXO-101 (ARRY-470) CAS NO.1223403-58-4

  • Min.Order: 1 Gram
  • Payment Terms: L/C
  • Product Details

Keywords

  • LOXO 101
  • LOXO101
  • ARRY-470

Quick Details

  • ProName: LOXO-101 (ARRY-470)
  • CasNo: 1223403-58-4
  • Molecular Formula: C21H22F2N6O2
  • Appearance: Solid powder
  • Application: Inhibitor
  • DeliveryTime: 7 days
  • ProductionCapacity: 10 Kilogram/Month
  • Purity: 98%
  • Storage: Dry, dark and at 0 - 4 C for short ter...
  • LimitNum: 1 Gram

Superiority

LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models. www.bocsci.com/loxo-101-arry-470-cas-1223403-58-4-item-470826.html

Details

LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models. www.bocsci.com/loxo-101-arry-470-cas-1223403-58-4-item-470826.html

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