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Home > Products >  GGTI 298 (trifluoroacetate salt)

GGTI 298 (trifluoroacetate salt) CAS NO.1217457-86-7

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Keywords

  • methyl (4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzoyl)-L-leucinate 2,2,2-trifluoroacetate
  • GGTI-298 TFA

Quick Details

  • ProName: GGTI 298 (trifluoroacetate salt)
  • CasNo: 1217457-86-7
  • Molecular Formula: C27H33N3O3S.CF3COOH
  • Appearance: White to off-white solid powder
  • Application: For research use only.
  • Purity: 95%
  • Storage: Store in a cool and dry place and at 0...
  • LimitNum: 0

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Details

GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells.

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