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Brigatinib (AP-26113) CAS NO.1197953-54-0
- Min.Order: 1 Gram
- Payment Terms: L/C
- Product Details
Keywords
- AP26113
- AP-26113
- Brigatinib
Quick Details
- ProName: Brigatinib (AP-26113)
- CasNo: 1197953-54-0
- Molecular Formula: C29H39ClN7O2P
- Appearance: Solid powder
- Application: Inhibitor
- DeliveryTime: 7 days
- ProductionCapacity: 10 Kilogram/Month
- Purity: 98%
- Storage: Dry, dark and at 0 - 4 C for short ter...
- LimitNum: 1 Gram
Superiority
Brigatinib, is an orally active, also known as AP-26113, potent and selective Dual ALK/EGFR inhibitor. AP26113 binds to and inhibits ALK kinase(ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development; ALK dysregulation and gene rearrangements are associated with a series of tumors. ), ALK fusion proteins, EGFR(EGFR is overexpressed in a variety of cancer cell types.) and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells. www.bocsci.com/brigatinib-ap-26113-cas-1197953-54-0-item-470820.html
Details
Brigatinib, is an orally active, also known as AP-26113, potent and selective Dual ALK/EGFR inhibitor. AP26113 binds to and inhibits ALK kinase(ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development; ALK dysregulation and gene rearrangements are associated with a series of tumors. ), ALK fusion proteins, EGFR(EGFR is overexpressed in a variety of cancer cell types.) and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells. www.bocsci.com/brigatinib-ap-26113-cas-1197953-54-0-item-470820.html