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Loureirin B CAS NO.119425-90-0
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Keywords
- 1-Propanone,1-(4-hydroxyphenyl)-3-(2,4,6-triMethoxyphenyl)
Quick Details
- ProName: Loureirin B
- CasNo: 119425-90-0
- Molecular Formula: C18H20O5
- Appearance: White powder
- Application: Analgesic/anti-inflammatory
- PackAge: 250 mg
- Purity: >98%
- LimitNum: 0
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Details
Loureirin B, isolated from the herbs of Dracaena cochinchinensis, is a channel blocker of Kv1.3 by interacting with amino acid residues in its selective filter region. Direct inhibition of Kv1.3 in T cells by SD and Loureirin B might be the cellular and molecular basis of SD-mediated immunosuppression. Loureirin B could evoke the elevation of [Ca(2+)](i) in a dose-dependent manner. Loureirin B is also the effective component in dragon's blood modulating sodium currents in trigeminal ganglion neurons.
