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2-Desamino-2-methylaminopterin CAS NO.118869-52-6
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Keywords
- dmAMT
- (4-(((4-amino-2-methylpteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid
Quick Details
- ProName: 2-Desamino-2-methylaminopterin
- CasNo: 118869-52-6
- Molecular Formula: C20H21N7O5
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
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Details
2-Desamino-2-methylaminopterin is an antifolate, and its polyglutamates are more potent than monoglutamate against three key enzymes of folate metabolism. It inhibits tumor cell growth in culture but is only a weak inhibitor of dihydrofolate reductase (DHFR).
