Quick Details
- ProName: Tripolin A
- CasNo: 1148118-92-6
- Molecular Formula: C15H11NO3
- Application: For research use only.
- Purity: 95%
- LimitNum: 0
Superiority
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Details
Tripolin A is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively. Tripolin A reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.