Keywords
- Q-VD-OPH
- Quinoline-Val-Asp-Difluorophenoxymethylketone
Quick Details
- ProName: Q-VD-OPH
- CasNo: 1135695-98-5
- Molecular Formula: C26H25F2N3O6
- Appearance: White to Off-white Solid Powder
- Application: For research use only.
- Purity: >98%
- Storage: Store at -20°C
- LimitNum: 0
Superiority
We provide customized and high-quality Q-VD-OPH product for your project.
Details
QVD-OPH, also known as Quinoline-Val-Asp-Difluorophenoxymethylketone, is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 (IC50 = 25nm), caspase-1 (IC50 = 50nM), caspase-8 (IC50 = 100nM) and caspase-9 (IC50 = 430nM). It can be used in Alzheimer's studies relating to caspase-6, the cysteinyl protease involved in neurodegenerative conditions. As well it is an intermediate in the formation of Palinavir, a potent HIV protease inhibitor.