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des-His1-[Glu9]-Glucagon (1-29) amide CAS NO.110084-95-2
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Keywords
- (Des-His1,Glu9)-Glucagon (1-29) amide (human, rat, porcine)
- H-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2
Quick Details
- ProName: des-His1-[Glu9]-Glucagon (1-29) amide
- CasNo: 110084-95-2
- Molecular Formula: C148H221N41O47S
- Appearance: White Lyophilized Solid
- Application: For research use only.
- Purity: ≥95%
- Storage: Store at -20°C
- LimitNum: 0
Superiority
We provide customized and high-quality des-His1-[Glu9]-Glucagon (1-29) amide product for your project.
Details
A glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes) that displays no agonist activity. It binds to glucagon receptors to stimulate breakdown of inositol phospholipids by phospholipase C. It was shown to potentiate glucose-stimulated pancreatic insulin release in vitro. It blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats.
