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Glasdegib CAS NO.1095173-27-5
- Min.Order: 1 Gram
- Payment Terms: L/C
- Product Details
Keywords
- 1095173-27-5
- PF-04449913
- stem cell
Quick Details
- ProName: Glasdegib
- CasNo: 1095173-27-5
- Molecular Formula: C21H22N6O
- Appearance: White Solid
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: >98%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduction. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model.