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2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine CAS NO.105650-23-5
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Keywords
- PhIP
- 1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine
Quick Details
- ProName: 2-Amino-1-methyl-6-phenylimidazo[4,5-b...
- CasNo: 105650-23-5
- Molecular Formula: C13H12N4
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
Superiority
We provide customized and high-quality 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine product for your project.
Details
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a food-derived carcinogen that is found in high temperature-cooked fish and meat. In humans, PhIP is metabolized by the cytochrome (CYP) P450 isoform CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts, which are directly correlated with increased risk of breast, colon, and prostate cancers.
