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Dolutegravir CAS NO.1051375-16-6
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- Product Details
Keywords
- cas 1051375-16-6
- S/GSK1349572
- 1051375-16-6
Quick Details
- ProName: Dolutegravir
- CasNo: 1051375-16-6
- Molecular Formula: C20H19F2N3O5
- Application: Dolutegravir (GSK1349572) is a two-met...
- DeliveryTime: 7 days
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- ProductionCapacity: Metric Ton/Day
- Purity: >98%
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- LimitNum: 0 Metric Ton
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Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI).
