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Methoctramine tetrahydrochloride CAS NO.104807-46-7
- Min.Order: 1 Gram
- Payment Terms: L/C
- Product Details
Keywords
- 104807-46-7
- cas 104807-46-7
- Methoctramine
Quick Details
- ProName: Methoctramine tetrahydrochloride
- CasNo: 104807-46-7
- Molecular Formula: C36H62N4O2·4HCl
- Appearance: Crystalline Solid
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: ≥95%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
Methoctramine is a selective M2 muscarinic acetylcholine receptor (mAChR) antagonist. Study shows that methoctramine inhibited the bradycardia induced by both vagal stimulation and ACh (ED50: 38 +/- 5 and 38 +/- 9 nmol kg-1, respectively), and facilitated vagally-induced bronchoconstriction (ED50: 58 +/- 5 nmol kg-1). At higher concentrations, methoctramine reduced responses to both nerve stimulation and exogenous ACh, indicating blockade of post-junctional muscarinic M3 receptors.