- Product Details
Keywords
- 104778-14-5
- cas 104778-14-5
- (3E)-3-[(3,4-dihydroxyphenyl)methylidene]-7-hydroxychromen-4-one
Quick Details
- ProName: Sappanone A
- CasNo: 104778-14-5
- Molecular Formula: C16H12O5
- Appearance: Solid Powder
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: ≥98%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
Sappanone A is a homoisoflavonoid isolated from the aerial parts of Caesalpinia sappan. It inhibited the production of nitric oxide (NO), prostaglandin E2 (PGE2) and interleukin-6 (IL-6) as well as the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and IL-6 in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Sappanone A exhibits anti-inflammatory effect via modulation of Nrf2 and NF-κB pathways.