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Isofistularin-3
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Keywords
- Isofistularin-3
Quick Details
- ProName: Isofistularin-3
- Molecular Formula: C31H30Br6N4O11
- Application: For research use only.
- Purity: ≥95%
- Storage: -20°C
- LimitNum: 0
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Details
Isofistularin-3 is a direct, DNA-competitive DNMT1 inhibitor, with an IC50 of 13.5 μM. Isofistularin-3, as a DNA demethylating agent, induces cell cycle arrest and sensitization to TRAIL in cancer cells. Isofistularin-3 can be used as an ADC cytotoxin.
