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5(S),6(R)-DiHETE CAS NO.82948-88-7
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Keywords
- (5S,6R,7E,9E,11Z,14Z)-5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid
Quick Details
- ProName: 5(S),6(R)-DiHETE
- CasNo: 82948-88-7
- Molecular Formula: C20H32O4
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
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Details
5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. 5(S),6(R)-DiHETE is a weak LTD4 receptor agonist in guinea pig lung membranes. It induces guinea pig ileum contraction with an ED50 value of 1.3 μM.
