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Rottlerin CAS NO.82-08-6
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Keywords
- 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone
Quick Details
- ProName: Rottlerin
- CasNo: 82-08-6
- Molecular Formula: C30H28O8
- Appearance: Brown to reddish brown (Solid)
- Application: Enzyme Inhibitors
- Purity: ≥98% (HPLC)
- Storage: Store in a cool and dry place (or refe...
- LimitNum: 0
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Details
Rottlerin, a principal phenolic compound of the Kamala plant Mallotus philippinensis, originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Recently, it has been shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively).
