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Antitrypanosomal agent 1 CAS NO.75144-12-6
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Keywords
- 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanone HCl
- NSC-304108
Quick Details
- ProName: Antitrypanosomal agent 1
- CasNo: 75144-12-6
- Molecular Formula: C11H14Cl3NO
- Appearance: White to Off-white Solid
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
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Details
Antitrypanosomal agent 1 is a potent and selective inhibitor of trypanothione reductase (TR), with an IC50 of 3.3 μM. It inhibits glutathione reductase (GR) (IC50 = 64.8 μM) and T. brucei (EC50 = 1 μM).
