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(±)-Praeruptorin A CAS NO.73069-25-7
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- Product Details
Keywords
- 2-Butenoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2Z)-rel-
- 2-Butenoic acid, 2-methyl-, 10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, [9α(Z),10α]-(±)-
Quick Details
- ProName: (±)-Praeruptorin A
- CasNo: 73069-25-7
- Molecular Formula: C21H22O7
- Appearance: White to Off-white Solid
- Application: anti-osteoclastogenic
- Purity: >98%
- Storage: Store at -20°C under inert atmosphere
- LimitNum: 0
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Details
(±)-Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis
