United States
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AS-041164 CAS NO.6318-41-8
- Min.Order: 1 Gram
- Payment Terms: L/C
- Product Details
Keywords
- 6318-41-8
- cas 6318-41-8
- 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione
Quick Details
- ProName: AS-041164
- CasNo: 6318-41-8
- Molecular Formula: C11H7NO4S
- Appearance: Yellow Solid
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: ≥98%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
The phosphatidylinositol 3-kinases (PI3Ks) are lipid and protein kinases involved in diverse biological processes, including cell growth, migration, and metabolism. AS-041164 is a highly potent and selective PI3Kγ inhibitor that inhibits PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ with IC50 values of 240 nM, 1.45 μM, 70 nM and 1.70 μM, respectively. It also blocks RANTES-induced neutrophil migration and displays anti-inflammatory activity in various in vivo rodent models.