Berteroin CAS NO.4430-42-6

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Berteroin is found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. It is a Erucin homolog that may exhibit antioxidative and anti-androgenic activities. Berteroin is an isothiocyanate (ITC) compound that decreases androgen receptor levels in prostate cancer cells. Berteroin also displays anti-inflammatory properties, decreasing LPS-induced release of pro-inflammatory cytokines in macrophages. It also decreases the release of pro-inflammatory cytokines in LPS-stimulated macrophages. It also suppresses IRAK degradation and phosphorylation of TAK1, p38 MAPK, ERK1/2, and Akt.