United States
Premiumsupplier
K 41498 CAS NO.434938-41-7
- Min.Order: 0
- Payment Terms:
- Product Details
Keywords
- D-Phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-norleucyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-α-glutamyl-L-lysyl-L-glu...
Quick Details
- ProName: K 41498
- CasNo: 434938-41-7
- Molecular Formula: C162H276N48O46
- Appearance: Off-white Powder
- Application: For research use only.
- Purity: >98%
- Storage: Store at -20°C
- LimitNum: 0
Superiority
We provide customized and high-quality K 41498 product for your project.
Details
K 41498 is a potent and highly selective CRF2 receptor antagonist. Its Ki values are 425, 0.66 and 0.62 nM for human CRF1, CRF2α and CRF2β receptors respectively. It prevents sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. It blocks urocortin-induced hypotension following systemic administration in rats in vivo and is used to treat hypertension in rodents.
