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Home > Products >  SW155246

SW155246 CAS NO.420092-79-1

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Keywords

  • 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide

Quick Details

  • ProName: SW155246
  • CasNo: 420092-79-1
  • Molecular Formula: C16H11ClN2O5S
  • Appearance: Crystalline Solid
  • Application: For research use only.
  • Purity: ≥98%
  • LimitNum: 0

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Details

SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1) with IC50 value of 1.2 μM, displaying 30-fold selectivity for inhibition of human DNMT1 versus human or murine DNMT3A or -3B. It was shown to inhibit global methylation in HeLa cells, and reactivate expression of the tumor suppressor gene RASSF1A in A549 cells.

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