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RFRP 3 (human) CAS NO.311309-27-0
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Keywords
- NPVF
- Neuropeptide VF (124-131) (human)
Quick Details
- ProName: RFRP 3 (human)
- CasNo: 311309-27-0
- Molecular Formula: C45H72N14O10
- Appearance: White to Off-white Powder
- Application: For research use only.
- Purity: ≥95% by HPLC
- Storage: Store at -20°C
- LimitNum: 0
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Details
RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization.
