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Orientin CAS NO.28608-75-5
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Keywords
- 8-b-D-Glucopyranosyl-3,4,7-tetrahydroxyflavone
- Luteolin 8-C-b-D-glucopyranoside
Quick Details
- ProName: Orientin
- CasNo: 28608-75-5
- Molecular Formula: C21H20O11
- Appearance: Yellow powder
- Application: Antidepressant
- PackAge: 250 mg
- Purity: >98%
- LimitNum: 0
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Details
Orientin, found in the herbs of Polygonum orientale Linn, exerts antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. Besides, Orientin may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway.
