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PF 06551600 malonate CAS NO.2140301-97-7
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Keywords
- 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one malate
Quick Details
- ProName: PF 06551600 malonate
- CasNo: 2140301-97-7
- Molecular Formula: C15H19N5O·C3H4O4
- Application: For research use only.
- Purity: ≥98% by HPLC
- LimitNum: 0
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We provide customized and high-quality PF 06551600 malonate product for your project.
Details
PF 06551600 is a potent and selective JAK3 inhibitor with IC50 value of 33.1 μM, exhibiting >1,000-fold selectivity over JAK1 and JAK2. It inhibits phosphorylation of STAT5, induced by IL-2, IL-4, IL-7 and IL-15. It also inhibits Th1 and Th17 T-cell differentiation and function in vitro.
