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JNJ-64619178 CAS NO.2086772-26-9
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Keywords
- (1S,2R,3S,5R)-3-[2-(2-Amino-3-bromoquinolin-7-yl)ethyl]-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol
Quick Details
- ProName: JNJ-64619178
- CasNo: 2086772-26-9
- Molecular Formula: C22H23BrN6O2
- Application: Enzyme Inhibitors
- Purity: 95%
- LimitNum: 0
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Details
JNJ-64619178 is a selective PRMT5 inhibitor with potent in vitro and in vivo activity. JNJ-64619178 binds simultaneously to the SAM- and protein substrate- binding pockets of the PRMT5/MEP50 complex with a pseudo-irreversible mode-of-action. It can be developed as the treatment of some malignancies.
