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Luotonin A CAS NO.205989-12-4
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Keywords
- Quino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one
Quick Details
- ProName: Luotonin A
- CasNo: 205989-12-4
- Molecular Formula: C18H11N3O
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
Luotonin A is an alkaloid isolated from a Chinese traditional herbal medicine Peganum nigellastrum. It binds to and stabilizes the topoisomerase I-DNA binary complex, leading to DNA breakage and cell death (IC50 = 5.07 - 12.6 μM).
