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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one CAS NO.199327-61-2
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Keywords
- Gefitinib Impurity 12
- 7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one
Quick Details
- ProName: 7-Methoxy-6-(3-morpholin-4-ylpropoxy)q...
- CasNo: 199327-61-2
- Molecular Formula: C16H21N3O4
- Appearance: White to Off-white Solid
- Application: For research use only.
- Purity: 95%
- Storage: Store at 2-8°C
- LimitNum: 0
Superiority
We provide customized and high-quality 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one product for your project.
Details
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is an intermediate of Gefitinib. Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition.
