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1-Naphthalenylsulfonyl-Ile-Trp-aldehyde CAS NO.161709-56-4
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Keywords
- N-(1-Naphthalenylsulfonyl)-Ile-Trp-aldehyde
- Pentanamide, N-[(1S)-1-formyl-2-(1H-indol-3-yl)ethyl]-3-methyl-2-[(1-naphthalenylsulfonyl)amino]-, (2S,3S)-
Quick Details
- ProName: 1-Naphthalenylsulfonyl-Ile-Trp-aldehyd...
- CasNo: 161709-56-4
- Molecular Formula: C27H29N3O4S
- Appearance: White to Off-white Powder
- Application: For research use only.
- Purity: ≥95%
- Storage: Store at -20°C
- LimitNum: 0
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Details
1-Naphthalenylsulfonyl-Ile-Trp-aldehyde is a potent, reversible, selective and cell-permeable cathepsin L inhibitor with an IC50 of 1.9 nM. It inhibits the release of bone Ca2+ and hydroxyproline in vitro and is useful in the treatment of osteoporosis.
