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RS 25344 CAS NO.152814-89-6
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Keywords
- RS-25344
- 1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
Quick Details
- ProName: RS 25344
- CasNo: 152814-89-6
- Molecular Formula: C19H13N5O4
- Appearance: White solid
- Application: For research use only.
- Purity: >98 %
- LimitNum: 0
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Details
RS 25344 is a potent and selective inhibitor of four cloned isoforms of PDE4 (A, B, C and D) and phosphorylated PDE4D (IC50 = 0.28, > 100, 160 and 330 nM at PDE4, PDE1, PDE2 and PDE3 respectively). It has been shown to inhibit eosinophil chemotaxis and increase progressive motility of spermatozoa in vitro.
