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QL-X-138 CAS NO.1469988-63-3
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Keywords
- N-(2-Methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide
Quick Details
- ProName: QL-X-138
- CasNo: 1469988-63-3
- Molecular Formula: C25H19N5O2
- Appearance: Solid powder
- Application: For research use only.
- Purity: ≥98% (HPLC)
- Storage: Store at -20°C
- LimitNum: 0
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Details
QL-X-138 is a potent and selective BTK/MNK dual kinase inhibitor, exhibiting covalent binding to BTK and non-covalent binding to MNK. QL-X-138 shows IC50s of 9.4 nM, 107.4 nM and 26 nM for BTK, MNK1 and MNK2 kinases respectively. QL-X-138 can be used for the research of B-cell malignancies.
