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CGP 52411 CAS NO.145915-58-8
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Keywords
- CGP 52411
- CGP52411
Quick Details
- ProName: CGP 52411
- CasNo: 145915-58-8
- Molecular Formula: C20H15N3O2
- Appearance: Yellow solid
- Application: Anti-Alzheimer agents; Amyloid-β inhib...
- Purity: 95%
- Storage: Store in a cool and dry place and at 0...
- LimitNum: 0
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Details
CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 μM) in neurons associated with Alzheimer's disease. And it is also a selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro).
