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LDN-212854 CAS NO.1432597-26-6
- Min.Order: 1 Gram
- Payment Terms: L/C
- Product Details
Keywords
- 1432597-26-6
- BMP Inhibitor III
- stem cell
Quick Details
- ProName: LDN-212854
- CasNo: 1432597-26-6
- Molecular Formula: C25H22N6
- Appearance: Solid Powder
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: >98%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
LDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2. LDN-212854 exhibits some selectivity for ALK2 in preference to other BMP type I receptors, ALK1 and ALK3, which may permit the interrogation of ALK2-mediated signaling, transcriptional activity, and function. LDN-212854 potently inhibits heterotopic ossification in an inducible transgenic mutant ALK2 mouse model of fibrodysplasia ossificans progressiva.