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5-(N,N-Hexamethylene)-amiloride CAS NO.1428-95-1
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- Product Details
Keywords
- Hexamethylene amiloride
- HMA
Quick Details
- ProName: 5-(N,N-Hexamethylene)-amiloride
- CasNo: 1428-95-1
- Molecular Formula: C12H18ClN7O
- Appearance: Solid Powder
- Application: For research use only.
- Purity: 0.98
- Storage: Powder:
-20°C: 3 years
4°C: 2 ... - LimitNum: 0
Superiority
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Details
5-(N,N-Hexamethylene)-amiloride derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. It is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively.
