IRL-1620 CAS NO.142569-99-1

We provide customized and high-quality IRL-1620 product for your project.

IRL-1620, also known as SPI-1620, is an endothelin B receptor agonist. SPI-1620 is a highly selective peptide agonist of the endothelin-B receptor. Endothelin B receptor agonist SPI-1620 binds to endothelin-B receptors on endothelial cells in tumor blood vessels, which, unlike the angioarchitecture of normal blood vessels, are relatively devoid of smooth muscle. This agent may induce a transient, selective increase in blood flow to a tumor, which may result in an increase in the delivery of anticancer agents to the tumor and, so, an increase in anticancer agent efficacy.