- Product Details
Keywords
- cas 1342278-01-6
- RKI 1447
- 1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea
Quick Details
- ProName: RKI-1447
- CasNo: 1342278-01-6
- Molecular Formula: C16H14N4O2S
- Appearance: Pale Yellow Solid
- Application: inhibitor
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: 98%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
RKI-1447 is a potent Rho-associated ROCK kinase inhibitor with IC50 values of 14.5 and 6.2 nM for ROCK1 and ROCK2 respectively. It exhibits significant anti-invasive and antitumor activity in breast cancer. RKI-1447 suppresses the activation of ROCK substrates MLC-2 and MYPT1.