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EMA401 CAS NO.1316755-16-4
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Keywords
- EMA 401
- EMA-401
Quick Details
- ProName: EMA401
- CasNo: 1316755-16-4
- Molecular Formula: C32H29NO5
- Appearance: Crystalline solid
- Application: For research use only.
- Purity: ≥ 95 %
- Storage: Sealed in dry, Store in freezer, under...
- LimitNum: 0
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Details
EMA401 is an orally bioavailable, potent and highly selective antagonist of the angiotensin II type 2 receptor (AT2; IC50s = 39.5 and 408,000 nM for rat recombinant AT2 and AT1, respectively). It inhibits capsaicin-induced calcium influx in cultured human dorsal root ganglion (hDRG) neurons (IC50 = 10 nM) and reduces neurite density and length in rat DRG neuronal cultures.
