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1-β-D-Arabinofuranosyluracil-2-C-methyl-d3,13C CAS NO.1256490-38-6
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Keywords
- 1-(2-C-Methyl-d3, 13C-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione
- 1-((2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyl-d3, 13C-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Quick Details
- ProName: 1-β-D-Arabinofuranosyluracil-2-C-methy...
- CasNo: 1256490-38-6
- Molecular Formula: C9[13C]H11D3N2O6
- Application: For research use only.
- Purity: 95%
- LimitNum: 0
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Details
1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C is the labeled analogue of 1-β-D-Arabinofuranosyluracil-2-C-methyl, an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
