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N-Desmethyl Enzalutamide CAS NO.1242137-16-1
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Keywords
- N-desmethylenzalutamide
- 1242137-16-1
Quick Details
- ProName: N-Desmethyl Enzalutamide
- CasNo: 1242137-16-1
- Molecular Formula: C20H14F4N4O2S
- Appearance: Off-white to white powder
- Application: the treatment of disorders involving a...
- PackAge: 20 mg
- Purity: 95%
- Storage: -20°C Freeze
- LimitNum: 0
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N-desmethyl Enzalutamide is a major metabolite of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist (IC50 = 36 nM) in LNCaP cells that inhibits the transcriptional activity of a mutant AR protein. Enzalutamide resists against induction of prostate-specific antigen (PSA) and transmembrane serine protease 2 (TMPRSS2). N-desmethyl Enzalutamide can be used for the treatment of disorders involving androgen, estrogen and progesterone receptors.
