Quick Details
- ProName: BML-278
- CasNo: 120533-76-8
- Molecular Formula: C24H25NO4
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
Superiority
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Details
BML-278 is a selective Sirt1 activator (EC150 = 1μM) structurally based on a dihydropyridine scaffold. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells.