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Avibactam Sodium Salt CAS NO.1192491-61-4
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Keywords
- sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[321]octan-6-yl sulfate
- NXL104
Quick Details
- ProName: Avibactam Sodium Salt
- CasNo: 1192491-61-4
- Molecular Formula: C7H10N3NaO6S
- Appearance: Solid powder
- Application: For research use only.
- PackAge: 500 mg
- Purity: 95%
- Storage: Store in a cool and dry place and at 0...
- LimitNum: 0
Superiority
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Details
Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens.
