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BW A868C CAS NO.118675-50-6
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Keywords
- BWA-868C
- BWA868C
Quick Details
- ProName: BW A868C
- CasNo: 118675-50-6
- Molecular Formula: C25H37N3O5
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors.
