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L-745870 hydrochloride CAS NO.1173023-36-3
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- Product Details
Keywords
- 1H-Pyrrolo(2,3-b)pyridine, 3-((4-(4-chlorophenyl)-1-piperazinyl)methyl)-, hydrochloride (1:1)
- 1-(4-chlorophenyl)-4-({1H-pyrrolo[2,3-b]pyridin-3-yl}methyl)piperazine hydrochloride
Quick Details
- ProName: L-745870 hydrochloride
- CasNo: 1173023-36-3
- Molecular Formula: C18H20Cl2N4
- Appearance: White Solid
- Application: For research use only.
- Purity: ≥95%
- Storage: Store at 2-8°C, sealed storage, away f...
- LimitNum: 0
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Details
L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active antagonist of dopamine D4 receptor (Ki = 0.43 nM). It exhibits weaker affinity for D2 (Ki = 960 nM) and D3 (Ki = 2300 nM) receptors, and moderate affinity for 5-HT2 receptors, sigma sites and α-adrenergic receptor.
