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Bisindolylmaleimide V CAS NO.113963-68-1
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Keywords
- BIM V
- Ro 31-6045
Quick Details
- ProName: Bisindolylmaleimide V
- CasNo: 113963-68-1
- Molecular Formula: C21H15N3O2
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
Bisindolylmaleimide IV (BIM IV) is a cell-permeable inhibitor of protein kinase C (PKC) with IC50 of 0.10-0.55 μM. It is a weak inhibitor of protein kinase C (PKC) demonstrating an IC50 value >100 μM. BIM IV also inhibits protein kinase A with IC50 of 2-11.8 μM. Bisindolylmaleimide V is used as a negative control for the PKC (protein kinase C)-inhibitory activity.
