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CB096 CAS NO.108883-90-5
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Keywords
- 2-Methoxy-4-(5-nitro-1H-benzo[d]imidazol-2-yl)phenol
Quick Details
- ProName: CB096
- CasNo: 108883-90-5
- Molecular Formula: C14H11N3O4
- Application: For research use only.
- Purity: 99%
- LimitNum: 0
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Details
CB096 selectively inhibited repeat associated non-ATG (RAN) translation and decreased the production of poly(GP) DPRs without affecting r(G4C2)66 mRNA levels in an HEK293T cellular model of c9ALS/FTD, alleviated dysfunctional nucleocytoplasmic transport, and selectively reduced the abundance of r(G4C2)66-induced stress granules.
