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ERRα antagonist-1 CAS NO.1072145-33-5
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Keywords
- N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
- ERRa antagonist-1
Quick Details
- ProName: ERRα antagonist-1
- CasNo: 1072145-33-5
- Molecular Formula: C21H19N3S2
- Application: For research use only.
- Purity: ≥95%
- Storage: Store at 2-8°C, protect from light
- LimitNum: 0
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Details
ERRα antagonist-1, a selective and high affinity antagonist of estrogen-related receptor α (ERRα), inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β with IC50s of 170 and 180 nM, respectively. It does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.
