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Home > Products >  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine CAS NO.105650-23-5

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Keywords

  • PhIP
  • 1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine

Quick Details

  • ProName: 2-Amino-1-methyl-6-phenylimidazo[4,5-b...
  • CasNo: 105650-23-5
  • Molecular Formula: C13H12N4
  • Appearance: Crystalline Solid
  • Application: For research use only.
  • Purity: ≥98%
  • LimitNum: 0

Superiority

We provide customized and high-quality 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine product for your project.

Details

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a food-derived carcinogen that is found in high temperature-cooked fish and meat. In humans, PhIP is metabolized by the cytochrome (CYP) P450 isoform CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts, which are directly correlated with increased risk of breast, colon, and prostate cancers.

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